BDBM50125151 1-(2-Amino-phenyl)-4-(7aS,11aR)-5,6,8,9,11,11a-hexahydro-4H,7aH-pyrido[3',4':4,5]pyrrolo[3,2,1-ij]quinolin-10-yl-butan-1-one::CHEMBL348977

SMILES Nc1ccccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3CCCN2c13

InChI Key InChIKey=MADYDKSIUUGPRY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125151   

Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125151(1-(2-Amino-phenyl)-4-(7aS,11aR)-5,6,8,9,11,11a-hex...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125151(1-(2-Amino-phenyl)-4-(7aS,11aR)-5,6,8,9,11,11a-hex...)
Affinity DataKi:  68nMAssay Description:Binding affinity towards DA D2 receptor using [3H]N-methyl-spiperone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125151(1-(2-Amino-phenyl)-4-(7aS,11aR)-5,6,8,9,11,11a-hex...)
Affinity DataKi:  106nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2C receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed