BDBM50125418 7-[(R)-2-((E)-3-Cyclohexyl-3-hydroxy-propenyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid::CHEMBL14530

SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O)C1CCCCC1

InChI Key InChIKey=RSHHWIMRRJFJJN-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50125418   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125418(7-[(R)-2-((E)-3-Cyclohexyl-3-hydroxy-propenyl)-5-o...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibitory activity against human EP4 receptor expressed in HEK293 ebna cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125418(7-[(R)-2-((E)-3-Cyclohexyl-3-hydroxy-propenyl)-5-o...)
Affinity DataKi: >1.30E+4nMAssay Description:Binding affinity towards IP receptor expressed in HEK293 ebna cells recombinantly expressing the corresponding human prostanoid cDNAsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125418(7-[(R)-2-((E)-3-Cyclohexyl-3-hydroxy-propenyl)-5-o...)
Affinity DataKi: >1.30E+4nMAssay Description:Binding affinity towards TP receptor expressed in HEK293 ebna cells recombinantly expressing the corresponding human prostanoid cDNAsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125418(7-[(R)-2-((E)-3-Cyclohexyl-3-hydroxy-propenyl)-5-o...)
Affinity DataKi: >1.30E+4nMAssay Description:Binding affinity towards EP2 receptor expressed in HEK293 ebna cells recombinantly expressing the corresponding human prostanoid cDNAsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125418(7-[(R)-2-((E)-3-Cyclohexyl-3-hydroxy-propenyl)-5-o...)
Affinity DataKi: >1.30E+4nMAssay Description:Binding affinity towards DP receptor expressed in HEK293 ebna cells recombinantly expressing the corresponding human prostanoid cDNAsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125418(7-[(R)-2-((E)-3-Cyclohexyl-3-hydroxy-propenyl)-5-o...)
Affinity DataKi: >1.30E+4nMAssay Description:Binding affinity towards EP3 receptor expressed in HEK293 ebna cells recombinantly expressing the corresponding human prostanoid cDNAsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125418(7-[(R)-2-((E)-3-Cyclohexyl-3-hydroxy-propenyl)-5-o...)
Affinity DataKi: >1.30E+4nMAssay Description:Binding affinity towards EP1 receptor expressed in HEK293 ebna cells recombinantly expressing the corresponding human prostanoid cDNAsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125418(7-[(R)-2-((E)-3-Cyclohexyl-3-hydroxy-propenyl)-5-o...)
Affinity DataKi: >1.30E+4nMAssay Description:Binding affinity towards FP receptor expressed in HEK293 ebna cells recombinantly expressing the corresponding human prostanoid cDNAsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed