BDBM50125614 5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-thiophen-2-yl-5H-furan-2-one::CHEMBL275650

SMILES CC1(O)OC(=O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1cccs1

InChI Key InChIKey=CTGPIHLEOYRNCV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125614   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125614(5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory of human Prostaglandin G/H synthase 2 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125614(5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory of human Prostaglandin G/H synthase 2 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125614(5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration was measured against Prostaglandin G/H synthase 1 in the sensitive U937 microsome assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed