BDBM50125615 5-Hydroxy-3-(4-isopropyl-phenyl)-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one::CHEMBL18867

SMILES CC(C)c1ccc(cc1)C1=C(c2ccc(cc2)S(C)(=O)=O)C(C)(O)OC1=O

InChI Key InChIKey=ILRGQKBXWMOPOJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125615   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125615(5-Hydroxy-3-(4-isopropyl-phenyl)-4-(4-methanesulfo...)
Affinity DataIC50: 410nMAssay Description:Inhibitory of human Prostaglandin G/H synthase 2 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125615(5-Hydroxy-3-(4-isopropyl-phenyl)-4-(4-methanesulfo...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory of human Prostaglandin G/H synthase 2 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125615(5-Hydroxy-3-(4-isopropyl-phenyl)-4-(4-methanesulfo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration was measured against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125615(5-Hydroxy-3-(4-isopropyl-phenyl)-4-(4-methanesulfo...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibitory concentration was measured against Prostaglandin G/H synthase 1 in the sensitive U937 microsome assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed