BDBM50125621 5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-(4-methylsulfanyl-phenyl)-5H-furan-2-one::CHEMBL277118

SMILES CSc1ccc(cc1)C1=C(c2ccc(cc2)S(C)(=O)=O)C(C)(O)OC1=O

InChI Key InChIKey=QSIMEXGETHTWEY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125621   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125621(5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-...)
Affinity DataIC50: 310nMAssay Description:Inhibitory of human Prostaglandin G/H synthase 2 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125621(5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory of human Prostaglandin G/H synthase 2 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125621(5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory concentration was measured against Prostaglandin G/H synthase 1 in the sensitive U937 microsome assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125621(5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibitory concentration was measured against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed