BDBM50125628 3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5-methoxy-5-methyl-5H-furan-2-one::CHEMBL18498

SMILES COC1(C)OC(=O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccc(F)cc1

InChI Key InChIKey=PBJWWPFSOCFQEE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125628   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125628(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 69nMAssay Description:Inhibitory of human Prostaglandin G/H synthase 2 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125628(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration was measured against Cyclooxygenase-2 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125628(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory concentration was measured against Prostaglandin G/H synthase 1 in the sensitive U937 microsome assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50125628(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibitory concentration was measured against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed