BDBM50125660 (2R,3S)-3-((S)-2-Benzoylamino-3-methyl-butyrylamino)-4-cyclohexyl-2-hydroxy-butyric acid ethyl ester::CHEMBL19901
SMILES CCOC(=O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@@H](NC(=O)c1ccccc1)C(C)C
InChI Key InChIKey=KCUIKGJJXJVGBL-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50125660
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of amyloid beta protein production in transfected H4 (neuroglioma) cells expressing APF constructs.More data for this Ligand-Target Pair
