BDBM50125705 4-[3-(2-Cyano-ethyl)-phenyl]-2,4-dioxo-butyric acid::CHEMBL20091

SMILES OC(=O)C(=O)CC(=O)c1cccc(CCC#N)c1

InChI Key InChIKey=FZYKLDPQTHCASB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125705   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50125705(4-[3-(2-Cyano-ethyl)-phenyl]-2,4-dioxo-butyric aci...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50125705(4-[3-(2-Cyano-ethyl)-phenyl]-2,4-dioxo-butyric aci...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50125705(4-[3-(2-Cyano-ethyl)-phenyl]-2,4-dioxo-butyric aci...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (3'processing)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed