BDBM50125733 6-Furan-2-yl-8a-hydroxymethyl-1,4-dioxo-2-(4-phenyl-butyl)-octahydro-pyrrolo[1,2-a]pyrazine-7-carboxylic acid phenyl ester::CHEMBL14000

SMILES OCC12CC(C(N1C(=O)CN(CCCCc1ccccc1)C2=O)c1ccco1)C(=O)Oc1ccccc1

InChI Key InChIKey=FWCXYHVYHGSMPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125733   

TargetHormone-sensitive lipase(Human)
Ontogen

Curated by ChEMBL
LigandPNGBDBM50125733(6-Furan-2-yl-8a-hydroxymethyl-1,4-dioxo-2-(4-pheny...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory activity against human hormone-sensitive lipase (HSL) expressed in the baculovirus was determined by p-nitrophenyl butyrate (PNPB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Ontogen

Curated by ChEMBL
LigandPNGBDBM50125733(6-Furan-2-yl-8a-hydroxymethyl-1,4-dioxo-2-(4-pheny...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibitory activity against Human Hormone-sensitive lipase (HSL) expressed in the baculovirus was determined by HSL [14 C] cholesteryl oleate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed