BDBM50125735 8a-Benzyloxymethyl-6-furan-2-yl-1,4-dioxo-2-(4-phenyl-butyl)-octahydro-pyrrolo[1,2-a]pyrazine-7-carboxylic acid 2-cyano-ethyl ester::CHEMBL14102

SMILES O=C(OCCC#N)C1CC2(COCc3ccccc3)N(C1c1ccco1)C(=O)CN(CCCCc1ccccc1)C2=O

InChI Key InChIKey=HLYBPBXTHCHLMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125735   

TargetHormone-sensitive lipase(Human)
Ontogen

Curated by ChEMBL
LigandPNGBDBM50125735(8a-Benzyloxymethyl-6-furan-2-yl-1,4-dioxo-2-(4-phe...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against human hormone-sensitive lipase (HSL) expressed in the baculovirus was determined by p-nitrophenyl butyrate (PNPB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Ontogen

Curated by ChEMBL
LigandPNGBDBM50125735(8a-Benzyloxymethyl-6-furan-2-yl-1,4-dioxo-2-(4-phe...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against Human Hormone-sensitive lipase (HSL) expressed in the baculovirus was determined by HSL [14 C] cholesteryl oleate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed