BDBM50126078 (3-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yloxy)-acetic acid::CHEMBL282190

SMILES CC(Cc1c[nH]c2c(OCC(O)=O)cccc12)NC[C@H](O)c1cccc(Cl)c1

InChI Key InChIKey=FHEYFIGWYQJVDR-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126078   

TargetBeta-3 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50126078((3-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamin...)
Affinity DataEC50:  0.110nMAssay Description:Agonistic activity against human Beta-3 adrenergic receptor as cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50126078((3-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamin...)
Affinity DataEC50:  0.0620nMAssay Description:Agonist activity at Homo sapiens (human) beta3 adrenoreceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50126078((3-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamin...)
Affinity DataEC50:  6.40nMAssay Description:Agonist activity at Homo sapiens (human) beta1 adrenoreceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50126078((3-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamin...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at Homo sapiens (human) beta2 adrenoreceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed