BDBM50126132 3-(1-Ethyl-4,4-dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile::CHEMBL417110

SMILES CCN1C(=S)OC(C)(C)c2cc(ccc12)-c1cc(F)cc(c1)C#N

InChI Key InChIKey=CFQMMYOYPCDNTL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126132   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50126132(3-(1-Ethyl-4,4-dimethyl-2-thioxo-1,4-dihydro-2H-be...)
Affinity DataIC50: 100nMAssay Description:Inhibition of [3H]P4 to progesterone receptor (PR) of human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50126132(3-(1-Ethyl-4,4-dimethyl-2-thioxo-1,4-dihydro-2H-be...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration on alkaline phosphatase activity in human T47D breast carcinoma cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed