BDBM50126133 3-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-methoxy-benzonitrile::CHEMBL25292

SMILES COc1cc(cc(c1)-c1ccc2NC(=S)OC(C)(C)c2c1)C#N

InChI Key InChIKey=CTTIMHOODJRMMQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126133   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50126133(3-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1...)
Affinity DataIC50: 100nMAssay Description:Inhibition of [3H]P4 binding at progesterone receptor of human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50126133(3-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration on alkaline phosphatase activity in human T47D breast carcinoma cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed