BDBM50126318 1-{2-[3-(4-Chloro-benzyl)-3H-imidazol-4-yl]-acetyl}-5-naphthalen-1-yl-1,2,3,6-tetrahydro-pyridine-4-carbonitrile::CHEMBL29619

SMILES Clc1ccc(Cn2cncc2CC(=O)N2CCC(C#N)=C(C2)c2cccc3ccccc23)cc1

InChI Key InChIKey=JHULRWOTZPYWRZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126318   

LigandPNGBDBM50126318(1-{2-[3-(4-Chloro-benzyl)-3H-imidazol-4-yl]-acetyl...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126318(1-{2-[3-(4-Chloro-benzyl)-3H-imidazol-4-yl]-acetyl...)
Affinity DataEC50: >100nMAssay Description:Inhibition of Ras farnesylation in Human Ha-Ras oncogene-transformed BALB/c 3T3 cells (EJ3 cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126318(1-{2-[3-(4-Chloro-benzyl)-3H-imidazol-4-yl]-acetyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of geranylgeranyltransferase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed