BDBM50126370 2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperazin-1-yl)methyl)-3,4-dihydronaphthalen-1(2H)-one::2-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-piperazin-1-ylmethyl)-3,4-dihydro-2H-naphthalen-1-one::CHEMBL28867

SMILES Fc1ccc(cc1)C(OCCN1CCN(CC2CCc3ccccc3C2=O)CC1)c1ccc(F)cc1

InChI Key InChIKey=GCZFLVUNYTXZNH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126370   

LigandPNGBDBM50126370(2-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-pip...)
Affinity DataKi:  57nMAssay Description:Binding affinity towards dopamine transporter (DAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126370(2-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-pip...)
Affinity DataKi:  57nMAssay Description:Displacement of [125I]RTI55 from DAT in rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126370(2-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-pip...)
Affinity DataKi:  110nMAssay Description:Binding affinity towards rat serotonin transporter (SERT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126370(2-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-pip...)
Affinity DataKi:  112nMAssay Description:Displacement of [125I]RTI55 from SERT in rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed