BDBM50126466 (6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-cyclopropyl-ethyl)-pyrrolidin-3-yl]-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione::CHEMBL33944

SMILES O=C1CN([C@@H]2CCN(CCC3CC3)C2)C(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@H](N12)c1ccc2OCOc2c1

InChI Key InChIKey=PKZJYZRNAZUWID-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126466   

LigandPNGBDBM50126466((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-cycl...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) obtained from human corpus cavernosum tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126466((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-cycl...)
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126466((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-cycl...)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed