BDBM50126600 1,3-Dimethyl-4-{methyl-[4-(pyridin-4-yloxy)-benzenesulfonyl]-amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL38180

SMILES CN(c1c(cnc2n(C)nc(C)c12)C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1

InChI Key InChIKey=XQRSTZJAXGSSTI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126600   

TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126600(1,3-Dimethyl-4-{methyl-[4-(pyridin-4-yloxy)-benzen...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloprotease 13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126600(1,3-Dimethyl-4-{methyl-[4-(pyridin-4-yloxy)-benzen...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against matrix metalloprotease 9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126600(1,3-Dimethyl-4-{methyl-[4-(pyridin-4-yloxy)-benzen...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against TACE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126600(1,3-Dimethyl-4-{methyl-[4-(pyridin-4-yloxy)-benzen...)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibitory activity against matrix metalloprotease 1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed