BDBM50126627 4-[(4-Methoxy-benzenesulfonyl)-methyl-amino]-8-vinyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL38106::N-hydroxy-4-(4-methoxy-N-methylphenylsulfonamido)-8-vinylquinoline-3-carboxamide

SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1c(cnc2c(C=C)cccc12)C(=O)NO

InChI Key InChIKey=JXIIDVGEPSOIKK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50126627   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126627(N-hydroxy-4-(4-methoxy-N-methylphenylsulfonamido)-...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against matrix metalloprotease 9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126627(N-hydroxy-4-(4-methoxy-N-methylphenylsulfonamido)-...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against matrix metalloprotease 13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50126627(N-hydroxy-4-(4-methoxy-N-methylphenylsulfonamido)-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50126627(N-hydroxy-4-(4-methoxy-N-methylphenylsulfonamido)-...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against matrix metalloprotease 1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126627(N-hydroxy-4-(4-methoxy-N-methylphenylsulfonamido)-...)
Affinity DataIC50: 205nMAssay Description:Inhibitory activity against TACE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed