BDBM50126631 4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-6-(trifluoromethyl)quinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-6-trifluoromethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL36021

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2ccc(cc12)C(F)(F)F)C(=O)NO

InChI Key InChIKey=BYFPJSOGSJVRJE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50126631   

TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126631(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-6-tri...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against matrix metalloprotease 13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126631(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-6-tri...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against matrix metalloprotease 9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126631(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-6-tri...)
Affinity DataIC50: 172nMAssay Description:Inhibitory activity against matrix metalloprotease 1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126631(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-6-tri...)
Affinity DataIC50: 174nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50126631(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-6-tri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against TACE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed