BDBM50126781 CHEMBL417680::Cyano-[5-fluoro-2-oxo-1-(4-trifluoromethyl-benzyl)-2,3-dihydro-1H-indol-3-yl]-acetic acid

SMILES OC(=O)C(C#N)C1C(=O)N(Cc2ccc(cc2)C(F)(F)F)c2ccc(F)cc12

InChI Key InChIKey=FTOPUXSQPJZAPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126781   

TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126781(Cyano-[5-fluoro-2-oxo-1-(4-trifluoromethyl-benzyl)...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed