BDBM50126812 8-Benzhydryloxy-3-benzyl-3-aza-bicyclo[3.2.1]octane::CHEMBL287016

SMILES C(N1CC2CCC(C1)C2OC(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50126812   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50126812(8-Benzhydryloxy-3-benzyl-3-aza-bicyclo[3.2.1]octan...)
Affinity DataIC50: 536nMAssay Description:Inhibition of [3H]WIN-35428 binding to the cocaine binding site on the dopamine transporter (DAT) in synaptosomal membrane preparations from rat stri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50126812(8-Benzhydryloxy-3-benzyl-3-aza-bicyclo[3.2.1]octan...)
Affinity DataIC50: 536nMAssay Description:Inhibition of [3H]WIN-35428 binding to the cocaine binding site on the dopamine transporter (DAT) in synaptosomal membrane preparations from rat stri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50126812(8-Benzhydryloxy-3-benzyl-3-aza-bicyclo[3.2.1]octan...)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of [3H]DA binding to DAT in rat striatal synaptosomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50126812(8-Benzhydryloxy-3-benzyl-3-aza-bicyclo[3.2.1]octan...)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of [3H]DA binding to DAT in rat striatal synaptosomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50126812(8-Benzhydryloxy-3-benzyl-3-aza-bicyclo[3.2.1]octan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter (5-HTT) in rat cortical tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50126812(8-Benzhydryloxy-3-benzyl-3-aza-bicyclo[3.2.1]octan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter (5-HTT) in rat cortical tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed