BDBM50126815 1-(4-iodobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperidine::4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(4-iodo-benzyl)-piperidine::CHEMBL284096

SMILES Fc1ccc(cc1)C(OCCC1CCN(Cc2ccc(I)cc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=NDGDCGDWGLUYKA-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50126815   

LigandPNGBDBM50126815(1-(4-iodobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)...)
Affinity DataKi:  2.10nMAssay Description:Affinity at rat dopamine transporter using [125I]RTI-55 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126815(1-(4-iodobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]RTI55 from DAT in rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126815(1-(4-iodobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)...)
Affinity DataKi:  13.6nMAssay Description:Inhibition of [3H]dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126815(1-(4-iodobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)...)
Affinity DataKi:  205nMAssay Description:Affinity at rat serotonin transporter using [125I]RTI-55 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126815(1-(4-iodobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)...)
Affinity DataKi:  205nMAssay Description:Displacement of [125I]RTI55 from SERT in rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50126815(1-(4-iodobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)...)
Affinity DataKi:  546nMAssay Description:Inhibition of [3H]norepinephrine uptake at the rat norepinephrine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126815(1-(4-iodobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of [3H]5-HT uptake at the rat serotonin transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed