BDBM50127027 CHEMBL3628255

SMILES Oc1ccc(cc1)-c1cnc2[nH]ccc2n1

InChI Key InChIKey=OPCDTRLJCLTNPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127027   

TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50127027(CHEMBL3628255)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127027(CHEMBL3628255)
Affinity DataIC50: 4.86E+3nMAssay Description:Inhibition of RIPK1 (unknown origin) using MBP substrate incubated for 2 hrs by ADP-Glo kinase function assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed