BDBM50127151 6-(2-Phenylsulfanyl-ethyl)-pteridine-2,4-diamine::CHEMBL50379

SMILES Nc1nc(N)c2nc(CCSc3ccccc3)cnc2n1

InChI Key InChIKey=OVPXUMDQGFGLQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127151   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50127151(6-(2-Phenylsulfanyl-ethyl)-pteridine-2,4-diamine |...)
Affinity DataIC50: 770nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed