BDBM50127154 5-((3,4-dichlorophenylamino)methyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::5-[(5,6,7,8-Tetrahydro-naphthalen-1-ylamino)-methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL48648

SMILES Nc1nc(N)c2c(CNc3cccc4CCCCc34)c[nH]c2n1

InChI Key InChIKey=CAYFHAJGILGDLV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127154   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50127154(5-[(5,6,7,8-Tetrahydro-naphthalen-1-ylamino)-methy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50127154(5-[(5,6,7,8-Tetrahydro-naphthalen-1-ylamino)-methy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50127154(5-[(5,6,7,8-Tetrahydro-naphthalen-1-ylamino)-methy...)
Affinity DataIC50: 5.93E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed