BDBM50127217 (E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-acrylic acid::CHEMBL40614

SMILES Cc1nc(sc1COc1ccc(\C=C\C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=MRQBQZNVLNJRQR-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50127217   

TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50127217((E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-p...)
Affinity DataEC50:  20nMAssay Description:Maximum transcriptional activation of human PPAR delta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50127217((E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity for human PPAR delta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50127217((E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-p...)
Affinity DataEC50:  2.70E+3nMAssay Description:Maximum transcriptional activation of human PPAR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50127217((E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-p...)
Affinity DataEC50:  3.20E+3nMAssay Description:Maximum transcriptional activation of human PPAR alpha receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed