BDBM50127407 5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-(3,5-difluoro-phenyl)-3-hydroxy-pentanoylamino]-3-methyl-butyrylamino}-cyclohexane-1,3-dicarboxylic acid dimethyl ester::CHEMBL296166

SMILES COC(=O)[C@H]1CC(C[C@H](C1)C(=O)OC)NC(=O)[C@H](NC(=O)C[C@H](O)[C@@H](Cc1cc(F)cc(F)c1)NC(=O)C(O)c1ccccc1-c1ccccc1)C(C)C

InChI Key InChIKey=GHUQZSZCASQUOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127407   

TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127407(5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed