BDBM50127437 CHEMBL52225::[1-(1-{1-[2-(1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-hydroxy-ethyl]-3-methyl-butylcarbamoyl}-3-methylsulfanyl-propylcarbamoyl)-2-methyl-propyl]-carbamic acid tert-butyl ester

SMILES CCCCNC(=O)[C@H](NC(=O)C[C@H](O)C(CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)C(C)C

InChI Key InChIKey=WCCQWNVMBPPQSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127437   

TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127437([1-(1-{1-[2-(1-Butylcarbamoyl-2-methyl-propylcarba...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed