BDBM50127653 1-(4-Methanesulfonyl-phenyl)-4,5-dihydro-3aH-naphtho[2,1-b]furan-2-one::CHEMBL44141

SMILES CS(=O)(=O)c1ccc(cc1)C1=C2C(CCc3ccccc23)OC1=O

InChI Key InChIKey=ZQCVEBOKAYTOSA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127653   

TargetProstaglandin G/H synthase 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50127653(1-(4-Methanesulfonyl-phenyl)-4,5-dihydro-3aH-napht...)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50127653(1-(4-Methanesulfonyl-phenyl)-4,5-dihydro-3aH-napht...)
Affinity DataIC50: 562nMAssay Description:In vitro inhibitory activity against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50127653(1-(4-Methanesulfonyl-phenyl)-4,5-dihydro-3aH-napht...)
Affinity DataIC50: 4.50E+4nMAssay Description:In vitro inhibitory activity against recombinant human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed