BDBM50127724 CHEMBL3629707

SMILES Cc1cc(cc2cn[nH]c12)C(=O)N1CC2(CN(C2)C(=O)OC(C)(C)C)C1

InChI Key InChIKey=MUXQLNFGXDGLJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127724   

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127724(CHEMBL3629707)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127724(CHEMBL3629707)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed