BDBM50128071 (4-(4-(4,5-dihydrooxazol-2-yl)benzylidene)piperidin-1-yl)(4-chlorophenyl)methanone::(4-Chloro-phenyl)-{4-[4-(4,5-dihydro-oxazol-2-yl)-benzylidene]-piperidin-1-yl}-methanone::(4-chlorophenyl)(4-(4-(4,5-dihydrooxazol-2-yl)benzylidene)piperidin-1-yl)methanone::CHEMBL417571

SMILES Clc1ccc(cc1)-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]\c1ccc(cc1)-[#6]-1=[#7]-[#6]-[#6]-[#8]-1

InChI Key InChIKey=VLADYICFJNKQFA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50128071   

TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128071((4-chlorophenyl)(4-(4-(4,5-dihydrooxazol-2-yl)benz...)
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128071((4-chlorophenyl)(4-(4-(4,5-dihydrooxazol-2-yl)benz...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase ERG7(Baker's yeast)
Università

Curated by ChEMBL
LigandPNGBDBM50128071((4-chlorophenyl)(4-(4-(4,5-dihydrooxazol-2-yl)benz...)
Affinity DataIC50: 670nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128071((4-chlorophenyl)(4-(4-(4,5-dihydrooxazol-2-yl)benz...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCycloartenol synthase(Mouse-ear cress)
Università

Curated by ChEMBL
LigandPNGBDBM50128071((4-chlorophenyl)(4-(4-(4,5-dihydrooxazol-2-yl)benz...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed