BDBM50128089 CHEMBL2369370::Tyr-Gly-Pro-Phe-Leu-Arg-NH2

SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#7])=O

InChI Key InChIKey=KAWQVYGFECGPRP-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128089   

TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50128089(Tyr-Gly-Pro-Phe-Leu-Arg-NH2 | CHEMBL2369370)
Affinity DataKi:  3.10E+3nMAssay Description:In vitro binding affinity towards human Opioid receptor kappa 1 on CHO cell membranes using [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50128089(Tyr-Gly-Pro-Phe-Leu-Arg-NH2 | CHEMBL2369370)
Affinity DataKi:  3.10E+3nMAssay Description:In vitro binding affinity to human Opioid receptor mu 1 on CHO cell membranes using [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50128089(Tyr-Gly-Pro-Phe-Leu-Arg-NH2 | CHEMBL2369370)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonistic activity in the Opioid receptor kappa 1 -mediated [35S]GTP-gamma-S, binding assay against 50 nM U-50,488More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50128089(Tyr-Gly-Pro-Phe-Leu-Arg-NH2 | CHEMBL2369370)
Affinity DataKi: >1.00E+5nMAssay Description:In vitro binding affinity to human Opioid receptor delta 1 on CHO cell membranes using [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed