BDBM50128358 CHEMBL3629347

SMILES CCCCC(NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O

InChI Key InChIKey=UAHFGYDRQSXQEB-UHFFFAOYSA-N

Data  1 KI  1 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50128358   

TargetMelanocortin receptor 5(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50128358(CHEMBL3629347)
Affinity DataEC50:  0.270nMAssay Description:Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells by AlphaScreen cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50128358(CHEMBL3629347)
Affinity DataEC50:  0.340nMAssay Description:Agonist activity at mouse melanocortin 4 receptor expressed in HEK293 cells by AlphaScreen cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50128358(CHEMBL3629347)
Affinity DataEC50:  0.220nMAssay Description:Agonist activity at mouse melanocortin 3 receptor expressed in HEK293 cells by AlphaScreen cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50128358(CHEMBL3629347)
Affinity DataEC50:  0.0190nMAssay Description:Agonist activity at mouse melanocortin 1 receptor expressed in HEK293 cells by AlphaScreen cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50128358(CHEMBL3629347)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human recombinant melanocortin 4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50128358(CHEMBL3629347)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at mouse MC5 receptor expressed in HEK293 cells after 2 hrs by cAMP alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50128358(CHEMBL3629347)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK293 cells after 2 hrs by cAMP alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50128358(CHEMBL3629347)
Affinity DataEC50:  0.470nMAssay Description:Agonist activity at mouse MC4 receptor expressed in HEK293 cells after 2 hrs by cAMP alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50128358(CHEMBL3629347)
Affinity DataEC50:  0.230nMAssay Description:Agonist activity at mouse MC3 receptor expressed in HEK293 cells after 2 hrs by cAMP alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50128358(CHEMBL3629347)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human recombinant melanocortin 4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed