BDBM50128360 CHEMBL3629480

SMILES Cc1c(Nc2ccc(cc2Cl)C#N)ncnc1OC1C2COCC1CN(C2)S(=O)(=O)C1CC1

InChI Key InChIKey=YVVXUESAUMDUNI-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128360   

TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50128360(CHEMBL3629480)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50128360(CHEMBL3629480)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50128360(CHEMBL3629480)
Affinity DataEC50:  844nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed