BDBM50128380 (S)-1-(1H-indol-4-yloxy)-3-(4-(benzo[b]thiophen-2-yl)piperidin-1-yl)propan-2-ol::(S)-1-(4-Benzo[b]thiophen-2-yl-piperidin-1-yl)-3-(1H-indol-4-yloxy)-propan-2-ol::CHEMBL300115

SMILES O[C@H](COc1cccc2[nH]ccc12)CN1CCC(CC1)c1cc2ccccc2s1

InChI Key InChIKey=YVOIIEQOIZEGMN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128380   

Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128380((S)-1-(4-Benzo[b]thiophen-2-yl-piperidin-1-yl)-3-(...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128380((S)-1-(4-Benzo[b]thiophen-2-yl-piperidin-1-yl)-3-(...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128380((S)-1-(4-Benzo[b]thiophen-2-yl-piperidin-1-yl)-3-(...)
Affinity DataKi:  16.8nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128380((S)-1-(4-Benzo[b]thiophen-2-yl-piperidin-1-yl)-3-(...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards serotonin [5-HT] reuptake site labeled with [3H]paroxetine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed