BDBM50128669 1-(4-Bromo-benzyl)-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-(4-bromobenzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::4-(4-but-2-ynyloxyphenylsulfanyl)piperidine-4-carboxylic acid hydroxyamide::CHEMBL78255

SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)C(=O)NO

InChI Key InChIKey=YMQWZRPLMNNHEU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50128669   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128669(4-(4-but-2-ynyloxyphenylsulfanyl)piperidine-4-carb...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128669(4-(4-but-2-ynyloxyphenylsulfanyl)piperidine-4-carb...)
Affinity DataIC50: 2nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50128669(4-(4-but-2-ynyloxyphenylsulfanyl)piperidine-4-carb...)
Affinity DataIC50: 72nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128669(4-(4-but-2-ynyloxyphenylsulfanyl)piperidine-4-carb...)
Affinity DataIC50: 598nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128669(4-(4-but-2-ynyloxyphenylsulfanyl)piperidine-4-carb...)
Affinity DataIC50: 598nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128669(4-(4-but-2-ynyloxyphenylsulfanyl)piperidine-4-carb...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128669(4-(4-but-2-ynyloxyphenylsulfanyl)piperidine-4-carb...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed