BDBM50128868 5-(2,4-Dichloro-phenoxy)-3-(2-fluoro-phenyl)-[1,2,4]triazolo[4,3-c]quinazoline::CHEMBL83231

SMILES Fc1ccccc1-c1nnc2c3ccccc3nc(Oc3ccc(Cl)cc3Cl)n12

InChI Key InChIKey=IKZFMOOVTIQLDS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128868   

TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50128868(5-(2,4-Dichloro-phenoxy)-3-(2-fluoro-phenyl)-[1,2,...)
Affinity DataKi:  1.18E+4nMAssay Description:Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50128868(5-(2,4-Dichloro-phenoxy)-3-(2-fluoro-phenyl)-[1,2,...)
Affinity DataKi:  2.88E+4nMAssay Description:Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50128868(5-(2,4-Dichloro-phenoxy)-3-(2-fluoro-phenyl)-[1,2,...)
Affinity DataKi:  4.81E+4nMAssay Description:Kinetic inhibition constant of compound with bacterial Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed