BDBM50128952 CHEMBL64367::{(S)-1-[2-(4-Cyclopropylmethoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCCNc1ccc(OCC2CC2)cc1

InChI Key InChIKey=FANVTDMKSBCCKF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128952   

TargetCathepsin K(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128952({(S)-1-[2-(4-Cyclopropylmethoxy-phenylamino)-ethyl...)
Affinity DataIC50: 69nMAssay Description:Inhibitory activity against recombinant human cathepsin K activity using fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128952({(S)-1-[2-(4-Cyclopropylmethoxy-phenylamino)-ethyl...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against recombinant human cathepsin S activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50128952({(S)-1-[2-(4-Cyclopropylmethoxy-phenylamino)-ethyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against recombinant human cathepsin L activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed