BDBM50129540 5-(2',4'-Dichloro-biphenyl-4-yl)-1-(2-hydroxy-ethyl)-1H-pyrazole-3-carboxylic acid::CHEMBL74009

SMILES OCCn1nc(cc1-c1ccc(cc1)-c1ccc(Cl)cc1Cl)C(O)=O

InChI Key InChIKey=LDQUUHYSEIMRAJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50129540   

TargetMethionine--tRNA ligase, cytoplasmic(Human)
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129540(5-(2',4'-Dichloro-biphenyl-4-yl)-1-(2-hydroxy-ethy...)
Affinity DataIC50: 4.46E+3nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Human)
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129540(5-(2',4'-Dichloro-biphenyl-4-yl)-1-(2-hydroxy-ethy...)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibitory activity against Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Human)
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129540(5-(2',4'-Dichloro-biphenyl-4-yl)-1-(2-hydroxy-ethy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed