BDBM50129969 CHEMBL74263::N-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropyl}-N-cyclopentyl-malonamic acid

SMILES Cn1c2ccc(cc2nc(Cc2ccc(cc2)C(N)=N)c1=O)C1(CC1)N(C1CCCC1)C(=O)CC(O)=O

InChI Key InChIKey=FXSYQODCNXHQNQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50129969   

TargetCoagulation factor X(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129969(N-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129969(N-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129969(N-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129969(N-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCoagulation factor X(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129969(N-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of coagulation factor Xa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTrypsin(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50129969(N-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,...)
Affinity DataIC50: 550nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlasminogen(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129969(N-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed