BDBM50129974 4-{7-[1-(2-Hydroxymethyl-pyrrolidine-1-carbonyl)-cyclopropyl]-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-ylmethyl}-benzamidine::CHEMBL307385

SMILES Cn1c2ccc(cc2nc(Cc2ccc(cc2)C(N)=N)c1=O)C1(CC1)C(=O)N1CCCC1CO

InChI Key InChIKey=QVZZKXUZNHHNMN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50129974   

TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129974(4-{7-[1-(2-Hydroxymethyl-pyrrolidine-1-carbonyl)-c...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129974(4-{7-[1-(2-Hydroxymethyl-pyrrolidine-1-carbonyl)-c...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129974(4-{7-[1-(2-Hydroxymethyl-pyrrolidine-1-carbonyl)-c...)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed