BDBM50129978 CHEMBL76068::[(1-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropanecarbonyl}-pyrrolidine-2-carbonyl)-amino]-acetic acid

SMILES Cn1c2ccc(cc2nc(Cc2ccc(cc2)C(N)=N)c1=O)C1(CC1)C(=O)N1CCCC1C(=O)NCC(O)=O

InChI Key InChIKey=VSAPBALCKYTRRE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50129978   

TargetProthrombin(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50129978([(1-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of Thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProthrombin(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50129978([(1-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50129978([(1-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlasminogen(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129978([(1-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129978([(1-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCoagulation factor X(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50129978([(1-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of coagulation factor Xa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCoagulation factor X(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50129978([(1-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed