BDBM50129982 (S)-2-(6-benzyl-5-chloro-2-oxo-3-(phenethylamino)pyrazin-1(2H)-yl)-N-(5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-yl)acetamide::2-(6-Benzyl-5-chloro-2-oxo-3-phenethylamino-2H-pyrazin-1-yl)-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide::CHEMBL308948

SMILES NC(=N)NCCC[C@H](NC(=O)Cn1c(Cc2ccccc2)c(Cl)nc(NCCc2ccccc2)c1=O)C(=O)c1nccs1

InChI Key InChIKey=VCHDSLCNSXYYJG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50129982   

TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129982((S)-2-(6-benzyl-5-chloro-2-oxo-3-(phenethylamino)p...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129982((S)-2-(6-benzyl-5-chloro-2-oxo-3-(phenethylamino)p...)
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129982((S)-2-(6-benzyl-5-chloro-2-oxo-3-(phenethylamino)p...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129982((S)-2-(6-benzyl-5-chloro-2-oxo-3-(phenethylamino)p...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129982((S)-2-(6-benzyl-5-chloro-2-oxo-3-(phenethylamino)p...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50129982((S)-2-(6-benzyl-5-chloro-2-oxo-3-(phenethylamino)p...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed