BDBM50129993 2-(((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)carbamoyl)-4-phenylbutyl(benzyl)phosphinic acid::Benzyl-[2-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-4-phenyl-butyl]-phosphinic acid::CHEMBL78233

SMILES CNC(=O)[C@@H](NC(=O)C(CCc1ccccc1)CP(O)(=O)Cc1ccccc1)C(C)(C)C

InChI Key InChIKey=ROFAQOFULLWONA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50129993   

TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129993(Benzyl-[2-((S)-2,2-dimethyl-1-methylcarbamoyl-prop...)
Affinity DataIC50: 12nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50129993(Benzyl-[2-((S)-2,2-dimethyl-1-methylcarbamoyl-prop...)
Affinity DataIC50: 93nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50129993(Benzyl-[2-((S)-2,2-dimethyl-1-methylcarbamoyl-prop...)
Affinity DataIC50: 93nMAssay Description:Inhibition of matrix metalloprotease-12More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129993(Benzyl-[2-((S)-2,2-dimethyl-1-methylcarbamoyl-prop...)
Affinity DataIC50: 110nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129993(Benzyl-[2-((S)-2,2-dimethyl-1-methylcarbamoyl-prop...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129993(Benzyl-[2-((S)-2,2-dimethyl-1-methylcarbamoyl-prop...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed