BDBM50130370 4-Imidazol-1-ylmethyl-2-[3-(1-methyl-2-oxo-azepan-3-yl)-phenoxy]-benzonitrile::CHEMBL318923

SMILES CN1CCCCC(c2cccc(Oc3cc(Cn4ccnc4)ccc3C#N)c2)C1=O

InChI Key InChIKey=JHPYFDJWXXWGRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130370   

LigandPNGBDBM50130370(4-Imidazol-1-ylmethyl-2-[3-(1-methyl-2-oxo-azepan-...)
Affinity DataIC50: 61nMAssay Description:Concentration required to inhibit recombinant human farnesyltransferase (FTase) catalyzed incorporation of [3H]FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50130370(4-Imidazol-1-ylmethyl-2-[3-(1-methyl-2-oxo-azepan-...)
Affinity DataIC50: 560nMAssay Description:Concentration required to inhibit recombinant human geranylgeranyl transferase type I (GGTase-I) catalyzed incorporation of [3H]GGPP to the C-terminu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed