BDBM50130607 3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-ethylidene]-17-azapentacyclo[7.5.3.210,14.01,10.02,7]nonadeca-2(7),3,5-trien-13-one::CHEMBL110124

SMILES COc1ccc2CC3N(C)CC[C@@]4([C@@H]5\C(C[C@]34CCC5=O)=C(/C)c3ccccc3)c2c1O

InChI Key

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50130607   

TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130607(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-eth...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity in recombinant human Opioid receptor kappa 1 transfected into chinese hamster ovary cells by displacing [3H]U-69593 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130607(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-eth...)
Affinity DataEC50:  3.40nMAssay Description:Agonistic activity towards Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130607(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-eth...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity for human Opioid receptor mu 1 transfected into chinese hamster ovary cells by displacing [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130607(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-eth...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity for human Opioid receptor delta 1 transfected into chinese hamster ovary cells by displacing [3H]CI-DPDPE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130607(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-eth...)
Affinity DataEC50:  15nMAssay Description:Effective concentration agonistic activity towards Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50130607(3-hydroxy-4-methoxy-17-methyl-18-[1-phenyl-(E)-eth...)
Affinity DataEC50:  72nMAssay Description:Agonistic activity towards Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed