BDBM50130953 2,4-Diamino-1,6-bis-(4-fluoro-phenyl)-[1,3,5]triazin-1-ium::CHEMBL309713

SMILES Nc1nc(-c2ccc(F)cc2)n(-c2ccc(F)cc2)c(=[NH2+])n1

InChI Key InChIKey=WZXDIDNXKGZFTJ-UHFFFAOYSA-O

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50130953   

TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50130953(2,4-Diamino-1,6-bis-(4-fluoro-phenyl)-[1,3,5]triaz...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50130953(2,4-Diamino-1,6-bis-(4-fluoro-phenyl)-[1,3,5]triaz...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50130953(2,4-Diamino-1,6-bis-(4-fluoro-phenyl)-[1,3,5]triaz...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed