BDBM50131041 2,3-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::CHEMBL315422

SMILES COc1cc2nc3-c4[nH]c5ccccc5c4CCn3c(=O)c2cc1OC

InChI Key InChIKey=SXNKSFFHUZYVSN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131041   

TargetCytochrome P450 1B1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131041(2,3-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyr...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human Cytochrome P450 1B1 expressed in bacterial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131041(2,3-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyr...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131041(2,3-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyr...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed