BDBM50131044 13H-Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::CHEMBL413956

SMILES O=c1c2ccccc2[nH]c2c3nc4ccccc4c3ccn12

InChI Key InChIKey=YSBDHHSWPXFVSR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131044   

TargetCytochrome P450 1A2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131044(13H-Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131044(13H-Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131044(13H-Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human Cytochrome P450 1B1 expressed in bacterial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed