BDBM50131176 CHEMBL3634539

SMILES Nc1n[nH]c2cccc(-c3ccc(cc3)C(=O)NCCNC(=O)c3ccccc3Br)c12

InChI Key InChIKey=OKHCJZLKVVFPLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131176   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50131176(CHEMBL3634539)
Affinity DataIC50: 31nMAssay Description:Inhibition of wild type Bcr-Abl (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50131176(CHEMBL3634539)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of Bcr-Abl T315I mutant (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed